《青少年网络游戏安全大数据报告》发布会在...
百度 有人只听说牛奶中有钙，看到酸奶没有标钙含量，就不知道该怎么选择钙含量高的酸奶产品了。
The scientific study of the structure and function of genes at the molecular level, particularly chromosomes and DNA.
16 questions from the last 365 days
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Confusion in concept of dominance and incomplete dominance
According to my textbook(NCERT)- out of two alleles one of them undergoes some changes(mutations I suppose) that leads to it making a normal/less efficient enzyme, a non functional enzyme or no enzyme ...
- 101
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What's the centromere effect on aging?
How does centromere decay contribute to aging?
I am curious about their restoration in somatic and/or reproductive cells
There are also candidates for "centromerase" analog of telomerase:
...
- 11
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Is it correct to call the DNase-treated sample the 'control' in Avery, MacLeod, and McCarty's experiment?
My high school biology teacher said that in Avery, MacLeod, and McCarty's experiment
Live R strain + DNA from heat killed S strain + DNase
is the control for this experiment, her explanation was that,
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I want full sequence of chromosome 21,want to locate some primers in that. Using this for downstream detection of trisomy 21. How will I do it ??????/
I want full sequence of chromosome 21, want to locate some primers in that. Using this for downstream detection of trisomy 21. How will I do it ?
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2
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Sequence of genes in specific cell lines
I'm looking for a way to check the sequences of specific genes in specific cell lines to determine if a specific gene in a specific cell line has a mutation for instance. I mean cell lines like MDA-MB-...
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87
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Modelling RNA translation
Are there formal or computational models of RNA translation that treat codons as virtual instructions in for example a ROM-like lookup table architecture?
I’m exploring analogies between embedded ...
user107347
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Do gene conversion events occur in recombinant strands that result from Holliday junctions resolved by opposite plane cuts?
Most articles or books I have read about gene conversion explain the mechanism of gene conversion by how the cuts resolve Holliday junction. For example according to this book, "Molecular ...
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Is there any case where dual expression of two separate recessively lethal genes leads to rescue?
I’m wondering if there are any known examples—either natural or synthetic—where two separate genes each have recessive alleles that are individually lethal, but when both genes are mutated ...
- 143
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How to find the HVRII locus on the Altai Neandertal
I am looking for the HVRII locus on the Altai Neandertal sequence. Its accession number is ERP002097, but it's the raw resequencing data so it is not on NCBI. You can download the relevant file (for ...
- 11
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47
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How were different reading frames translated in repeating poly-trinucleotide RNA sequences?
In foundational experiments by Har Gobind Khorana and colleagues during the 1960s, synthetic polyribonucleotides were used to decipher the genetic code using in vitro cell-free protein synthesis ...
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Is a start codon on the mRNA required for cell-free translation initiation?
I just took an exam for my Introduction to Molecular Biology and Genetics, where there was a question that referenced Khorana's experiments to determine the sequence of the stop codon. The question is ...
- 143
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qPCR primer not showing any results
I am using a primer that was used before (not by me) and shown results for the same species of nematodes that I am studying. I made sure that the primer aligns to the nematode's genome through ...
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44
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How to balance PCR template amounts between high and low gene copy targets?
In eukaryotic DNA metabarcoding, whether you use a mitochondrial (e.g. COI, 12S, 16S) or a nuclear (e.g. 18S) marker gene will affect your yield for different reasons. Often it is recommended to use a ...
- 101
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116
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How to test whether correlation of couples phenotypes is due to assortative mating or environment?
A few phenotypes are easier to pinpoint as assortative mating (height for example), But other phenotypes such as vitamin D, weight, etc could be a combination of shared environment and assortative ...
- 121
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Troubleshooting agarose gel electrophoresis - Loading dye and DNA samples moving in opposite directions
The students of my Genetics class and I (instructor) are experiencing a systematic issue with our agarose gel electrophoreses which we cannot explain. We are looking for ideas that could explain our ...
